Journal: Clinical and Translational Science

Article Title: Leukocyte cell‐derived chemotaxin 2 correlates with pediatric non‐alcoholic fatty liver disease

doi: 10.1111/cts.13666

Figure Lengend Snippet: Patient characteristics.

Article Snippet: Serum LECT2 concentrations were quantified using commercially available human LECT2 enzyme‐linked immunosorbent assay (ELISA) kits (human leukocyte cell‐derived chemotaxin 2 [LECT2] ELISA Kit, Cat#EKU05623; Biomatik; Cambridge, Ontario, Canada).

Techniques:

Journal: Clinical and Translational Science

Article Title: Leukocyte cell‐derived chemotaxin 2 correlates with pediatric non‐alcoholic fatty liver disease

doi: 10.1111/cts.13666

Figure Lengend Snippet: Serum leukocyte cell‐derived chemotaxin 2 (LECT2) levels in pediatric non‐alcoholic fatty liver disease (NAFLD) patients and controls. (a) Boxplot comparison of LECT2 concentration (ng/mL) in pediatric controls and those with NAFLD. Difference in means between controls and NAFLD, p < 0.005. The horizontal line denotes median value; box extends from the 25th to the 75th percentile of the distribution; vertical lines denote smallest and largest values; and dots denote outliers. (b) Boxplot comparison of LECT2 concentration (ng/mL) in pediatric controls and those with NAFLD group by sex. Difference in means between controls and NAFLD in females, p = 0.03, and males, p = 0.017. The horizontal line denotes median value; box extends from the 25th to the 75th percentile of the distribution; vertical lines denote smallest and largest values; and dots denote outliers.

Article Snippet: Serum LECT2 concentrations were quantified using commercially available human LECT2 enzyme‐linked immunosorbent assay (ELISA) kits (human leukocyte cell‐derived chemotaxin 2 [LECT2] ELISA Kit, Cat#EKU05623; Biomatik; Cambridge, Ontario, Canada).

Techniques: Derivative Assay, Concentration Assay

Journal: Clinical and Translational Science

Article Title: Leukocyte cell‐derived chemotaxin 2 correlates with pediatric non‐alcoholic fatty liver disease

doi: 10.1111/cts.13666

Figure Lengend Snippet: Serum leukocyte cell‐derived chemotaxin 2 (LECT2) levels and their correlations with body mass index (BMI) and common markers of liver disease. (a) Scatterplot of pediatric LECT2 concentration (ng/mL) to BMI (kg/m 2 ) ( n = 105, Pearson r = 0.301, p = 0.002). (b) Scatterplot of pediatric LECT2 concentration (ng/mL) to BMI z‐score ( n = 105, Pearson r = 0.412, p < 0.005). (c) Scatterplot of pediatric LECT2 concentration (ng/mL) to alanine aminotransferase (ALT) (U/L) ( n = 105, Pearson r = 0.177, p = 0.071). (d) Scatterplot of pediatric LECT2 concentration (ng/mL) to aspartate aminotransferase (AST) (U/L) ( n = 105, Pearson r = 0.093, p = 0.345).

Article Snippet: Serum LECT2 concentrations were quantified using commercially available human LECT2 enzyme‐linked immunosorbent assay (ELISA) kits (human leukocyte cell‐derived chemotaxin 2 [LECT2] ELISA Kit, Cat#EKU05623; Biomatik; Cambridge, Ontario, Canada).

Techniques: Derivative Assay, Concentration Assay

Journal: Clinical and Translational Science

Article Title: Leukocyte cell‐derived chemotaxin 2 correlates with pediatric non‐alcoholic fatty liver disease

doi: 10.1111/cts.13666

Figure Lengend Snippet: Receiver operating characteristic (ROC) curve of leukocyte cell‐derived chemotaxin 2 (LECT2) to predict non‐alcoholic fatty liver disease (NAFLD) ( n = 105, p < 0.005).

Article Snippet: Serum LECT2 concentrations were quantified using commercially available human LECT2 enzyme‐linked immunosorbent assay (ELISA) kits (human leukocyte cell‐derived chemotaxin 2 [LECT2] ELISA Kit, Cat#EKU05623; Biomatik; Cambridge, Ontario, Canada).

Techniques: Derivative Assay

Journal: Clinical and Translational Science

Article Title: Leukocyte cell‐derived chemotaxin 2 correlates with pediatric non‐alcoholic fatty liver disease

doi: 10.1111/cts.13666

Figure Lengend Snippet: Principal component analysis (PCA) of the variables alanine aminotransferase (ALT), leukocyte cell‐derived chemotaxin 2 (LECT2), gender, and race/ethnicity. PCA plots showing (a) gender, non‐alcoholic fatty liver disease (NAFLD) status, and LECT2 levels; (b) race/ethnicity, NAFLD status, and LECT2 levels; (c) gender, NAFLD status, and body mass index (BMI); and (d) race/ethnicity, NAFLD status, and BMI.

Article Snippet: Serum LECT2 concentrations were quantified using commercially available human LECT2 enzyme‐linked immunosorbent assay (ELISA) kits (human leukocyte cell‐derived chemotaxin 2 [LECT2] ELISA Kit, Cat#EKU05623; Biomatik; Cambridge, Ontario, Canada).

Techniques: Derivative Assay

Journal: Clinical and Translational Science

Article Title: Leukocyte cell‐derived chemotaxin 2 correlates with pediatric non‐alcoholic fatty liver disease

doi: 10.1111/cts.13666

Figure Lengend Snippet: Summary table of logistic regression model showing beta estimate together with beta 95% confidence interval, standard error, and significant test using the z statistic for each variable.

Article Snippet: Serum LECT2 concentrations were quantified using commercially available human LECT2 enzyme‐linked immunosorbent assay (ELISA) kits (human leukocyte cell‐derived chemotaxin 2 [LECT2] ELISA Kit, Cat#EKU05623; Biomatik; Cambridge, Ontario, Canada).

Techniques:

Journal: Clinical and Translational Science

Article Title: Leukocyte cell‐derived chemotaxin 2 correlates with pediatric non‐alcoholic fatty liver disease

doi: 10.1111/cts.13666

Figure Lengend Snippet: Box and whisker plot depicting leukocyte cell‐derived chemotaxin 2 (LECT2) levels, stratified by gender. Each datapoint denotes an individual patient, with point shape indicating race/ethnicity and color denoting disease status.

Article Snippet: Serum LECT2 concentrations were quantified using commercially available human LECT2 enzyme‐linked immunosorbent assay (ELISA) kits (human leukocyte cell‐derived chemotaxin 2 [LECT2] ELISA Kit, Cat#EKU05623; Biomatik; Cambridge, Ontario, Canada).

Techniques: Whisker Assay, Derivative Assay